The co-receptor signaling model of HIV-1 pathogenesis in peripheral CD4 T cells

<p>Abstract</p> <p>HIV-mediated CD4 depletion is the hallmark of AIDS and is the most reliable predictor of disease progression. While HIV replication is associated with CD4 depletion in general, plasma viremia by itself predicts the rate of CD4 loss only minimally in untreated pat...

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Bibliographic Details
Main Author: Wu Yuntao
Format: Article
Language:English
Published: BMC 2009-05-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/6/1/41