The co-receptor signaling model of HIV-1 pathogenesis in peripheral CD4 T cells
<p>Abstract</p> <p>HIV-mediated CD4 depletion is the hallmark of AIDS and is the most reliable predictor of disease progression. While HIV replication is associated with CD4 depletion in general, plasma viremia by itself predicts the rate of CD4 loss only minimally in untreated pat...
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Format: | Article |
Language: | English |
Published: |
BMC
2009-05-01
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Series: | Retrovirology |
Online Access: | http://www.retrovirology.com/content/6/1/41 |