Vancomycin-loaded oxidized hyaluronic acid and adipic acid dihydrazide hydrogel: Bio-compatibility, drug release, antimicrobial activity, and biofilm model

Background: Prosthesis infection is a difficult-to-treat situation. Hydrogel is a novel biomaterial, which can be applied by simply spraying or by coating on implants before surgery and can be easily mixed with antibiotics. Methods: In order to evaluate the potential use of antibiotic-loaded hydroge...

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Bibliographic Details
Main Authors: Chun-Hsing Liao, Chiang Sang Chen, Yu-Chun Chen, Ni-En Jiang, Chui Jia Farn, Yi-Shan Shen, Ming-Lun Hsu, Chih-Hung Chang
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Journal of Microbiology, Immunology and Infection
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1684118219301410