Generation of stable advective-diffusive chemokine gradients in a three-dimensional hydrogel
Physiologic chemoattractant gradients are shaped by diffusion, advection, binding to an extracellular matrix, and removal by cells. Previous in vitro tools for studying these gradients and the cellular migratory response have required cells to be constrained to a 2D substrate or embedded in a gel de...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
AIP Publishing LLC
2022-02-01
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| Series: | AIP Advances |
| Online Access: | http://dx.doi.org/10.1063/5.0064947 |