Delivery Approaches for Therapeutic Genome Editing and Challenges

Impressive therapeutic advances have been possible through the advent of zinc-finger nucleases and transcription activator-like effector nucleases. However, discovery of the more efficient and highly tailorable clustered regularly interspaced short palindromic repeats (CRISPR) and associated protein...

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Bibliographic Details
Main Authors: Ilayda Ates, Tanner Rathbone, Callie Stuart, P. Hudson Bridges, Renee N. Cottle
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/11/10/1113