A Novel Metastatic Estrogen Receptor-Expressing Breast Cancer Model with Antiestrogen Responsiveness

A Novel Metastatic Estrogen Receptor-Expressing Breast Cancer Model with Antiestrogen Responsiveness

Most women diagnosed with breast cancer (BC) have estrogen receptor alpha-positive (ER+) disease. The current mouse models of ER+ BC often rely on exogenous estrogen to encourage metastasis, which modifies the immune system and the function of some tissues like bone. Other studies use genetically mo...

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Bibliographic Details
Main Authors: Kendall L. Langsten, Lihong Shi, Adam S. Wilson, Salvatore Lumia, Brian Westwood, Alexandra M. Skeen, Maria T. Xie, Victoria E. Surratt, JoLyn Turner, Carl D. Langefeld, Ravi Singh, Katherine L. Cook, Bethany A. Kerr
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Cancers
Subjects:
estrogen receptor alpha
metastasis
bone metastasis
antiestrogen treatment
Online Access:https://www.mdpi.com/2072-6694/15/24/5773

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https://www.mdpi.com/2072-6694/15/24/5773

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