Proliferation through activation: hemophagocytic lymphohistiocytosis in hematologic malignancy

Proliferation through activation: hemophagocytic lymphohistiocytosis in hematologic malignancy

Abstract: Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of cytokine-driven immune activation. Cardinal features include fever, hemophagocytosis, hepatosplenomegaly, lymphocytic infiltration, and hypercytokinemia that result in multisystem organ dysfunction and failure. Familial HLH is genet...

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Bibliographic Details
Main Authors: Eric J. Vick, Kruti Patel, Philippe Prouet, Mike G. Martin
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952920301877

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http://www.sciencedirect.com/science/article/pii/S2473952920301877

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