Phase-Dependent Adsorption of Myelin Basic Protein to Phosphatidylcholine Lipid Bilayers

Phase-Dependent Adsorption of Myelin Basic Protein to Phosphatidylcholine Lipid Bilayers

The dense packing of opposite cytoplasmic surfaces of the lipid-enriched myelin membrane, responsible for the proper saltatory conduction of nerve impulses through axons, is ensured by the adhesive properties of myelin basic protein (MBP). Although preferentially interacting with negatively charged...

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Bibliographic Details
Main Authors: Petra Maleš, Zlatko Brkljača, Ivo Crnolatac, Dražen Petrov, Danijela Bakarić
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Membranes
Subjects:
myelin basic protein (MBP)
1,2-dipalmitoyl-<i>sn</i>-glycero-3-phosphocholine (DPPC)
lipid phase-dependent hydration of MBP hydrophobic amino acids
spectroscopic (UV-Vis, FTIR, CD) and calorimetric (DSC) measurements
molecular dynamics (MD) simulations
Online Access:https://www.mdpi.com/2077-0375/14/1/15

Internet

https://www.mdpi.com/2077-0375/14/1/15

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