Disentangling pharmacological and expectation effects in antidepressant discontinuation among patients with fully remitted major depressive disorder: study protocol of a randomized, open-hidden discontinuation trial

Disentangling pharmacological and expectation effects in antidepressant discontinuation among patients with fully remitted major depressive disorder: study protocol of a randomized, open-hidden discontinuation trial

Abstract Background Antidepressants are established as an evidence-based, guideline-recommended treatment for Major Depressive Disorder. Prescriptions have markedly increased in past decades, with a specific surge in maintenance prescribing. Patients often remain on antidepressants longer than clini...

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Bibliographic Details
Main Authors: Carina Meißner, Claire Warren, Tahmine Fadai, Amke Müller, Antonia Zapf, Susanne Lezius, Ann-Kathrin Ozga, Irina Falkenberg, Tilo Kircher, Yvonne Nestoriuc
Format: Article
Language:English
Published: BMC 2023-06-01
Series:BMC Psychiatry
Subjects:
Depressive disorder
Psychotropic drugs
Drug tapering
Treatment expectation
Nocebo effect
Online Access:https://doi.org/10.1186/s12888-023-04941-3

Internet

https://doi.org/10.1186/s12888-023-04941-3

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