Myeloid-derived suppressor cells in peripheral blood as predictive biomarkers in patients with solid tumors undergoing immune checkpoint therapy: systematic review and meta-analysis

Myeloid-derived suppressor cells in peripheral blood as predictive biomarkers in patients with solid tumors undergoing immune checkpoint therapy: systematic review and meta-analysis

BackgroundImmunotherapeutic approaches, including immune checkpoint inhibitor (ICI) therapy, are increasingly recognized for their potential. Despite notable successes, patient responses to these treatments vary significantly. The absence of reliable predictive and prognostic biomarkers hampers the...

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Bibliographic Details
Main Authors: Maximilian Möller, Vanessa Orth, Viktor Umansky, Svetlana Hetjens, Volker Braun, Christoph Reißfelder, Julia Hardt, Steffen Seyfried
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-05-01
Series:Frontiers in Immunology
Subjects:
immune checkpoint inhibitors
immunotherapy
myeloid-derived suppressor cells
MDSC
neoplasms
solid malignancies
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1403771/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1403771/full

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