System-wide analyses reveal essential roles of N-terminal protein modification in bacterial membrane integrity
Summary: The removal of the N-terminal formyl group on nascent proteins by peptide deformylase (PDF) is the most prevalent protein modification in bacteria. PDF is a critical target of antibiotic development; however, its role in bacterial physiology remains a long-standing question. This work used...
Egile Nagusiak: | , , , , , |
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Formatua: | Artikulua |
Hizkuntza: | English |
Argitaratua: |
Elsevier
2022-08-01
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Saila: | iScience |
Gaiak: | |
Sarrera elektronikoa: | http://www.sciencedirect.com/science/article/pii/S2589004222010288 |