Agonist bias and agonist‐dependent antagonism at corticotrophin releasing factor receptors
Abstract The corticotropin‐releasing factor (CRF) receptors represent potential drug targets for the treatment of anxiety, stress, and other disorders. However, it is not known if endogenous CRF receptor agonists display biased signaling, how effective CRF receptor antagonists are at blocking differ...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2020-06-01
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Series: | Pharmacology Research & Perspectives |
Subjects: | |
Online Access: | https://doi.org/10.1002/prp2.595 |