Delayed angiopoietin‐2 blockade reduces influenza‐induced lung injury and improves survival in mice

Abstract Influenza remains a major cause of death and disability with limited treatment options. Studies of acute lung injury have identified angiopoietin‐2 (Ang‐2) as a key prognostic marker and a potential mediator of Acute respiratory distress syndrome. However, the role of Ang‐2 in viral pneumon...

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Bibliographic Details
Main Authors: Jeffrey E. Gotts, Mazharul Maishan, Lauren Chun, Xiaohui Fang, Chun‐Ya Han, Venice Chiueh, Aarif Y. Khakoo, TaeWeon Lee, Marina Stolina, Michael A. Matthay
Format: Article
Language:English
Published: Wiley 2021-11-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.15081