Local circuit allowing hypothalamic control of hippocampal area CA2 activity and consequences for CA1

Local circuit allowing hypothalamic control of hippocampal area CA2 activity and consequences for CA1

The hippocampus is critical for memory formation. The hypothalamic supramammillary nucleus (SuM) sends long-range projections to hippocampal area CA2. While the SuM-CA2 connection is critical for social memory, how this input acts on the local circuit is unknown. Using transgenic mice, we found that...

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Bibliographic Details
Main Authors: Vincent Robert, Ludivine Therreau, Vivien Chevaleyre, Eude Lepicard, Cécile Viollet, Julie Cognet, Arthur JY Huang, Roman Boehringer, Denis Polygalov, Thomas J McHugh, Rebecca Ann Piskorowski
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-05-01
Series:eLife
Subjects:
hippocampus
supramammillary nucleus
area CA2
hippocampal circuitry
inhibition
social memory
Online Access:https://elifesciences.org/articles/63352

Internet

https://elifesciences.org/articles/63352

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