Detection of derivative 9 deletion by BCR-ABL fluorescence in-situ hybridization signal pattern to evaluate treatment response in CML patients

Detection of derivative 9 deletion by BCR-ABL fluorescence in-situ hybridization signal pattern to evaluate treatment response in CML patients

Background: To evaluate prognostic effect of submicroscopic deletions involving breakage and fusion points of the derivative chromosome 9 and 22 in chronic myeloid leukemia in untreated patients and their follow up samples to correlate with disease outcome. Methods: The study included 78 pretreatmen...

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Bibliographic Details
Main Authors: Bakshi Sonal R., Shah Pankaj M., Shukla Shilin N., Dalal Esha N., Iyer Ramesh R., Brahmbhatt Manisha M., Gajjar Sarju B., Trivedi Pina J., Patel Beena P.
Format: Article
Language:English
Published: Institute of Oncology, Sremska Kamenica, Serbia 2009-01-01
Series:Archive of Oncology
Subjects:
Leukemia
Myelogenous
Chronic
BCR-ABL Positive
Myeloid
Chronic-Phase
Fusion Proteins
BCR-ABL
Treatment Outcome
Chromosomes
Human
Pair 9
Chromosome Deletion
Genes
abl
In Situ Hybridization
Fluorescence
Online Access:http://www.doiserbia.nb.rs/img/doi/0354-7310/2009/0354-73100902013P.pdf

Internet

http://www.doiserbia.nb.rs/img/doi/0354-7310/2009/0354-73100902013P.pdf

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