Aberrant translation regulated by METTL1/WDR4‐mediated tRNA N7‐methylguanosine modification drives head and neck squamous cell carcinoma progression

Aberrant translation regulated by METTL1/WDR4‐mediated tRNA N7‐methylguanosine modification drives head and neck squamous cell carcinoma progression

Abstract Background Cancer cells selectively promote the translation of oncogenic transcripts to stimulate cancer progression. Although growing evidence has revealed that tRNA modifications and related genes participate in this process, their roles in head and neck squamous cell carcinoma (HNSCC) re...

Full description

Bibliographic Details
Main Authors: Jie Chen, Kang Li, Jianwen Chen, Xiaochen Wang, Rongsong Ling, Maosheng Cheng, Zhi Chen, Fangfang Chen, Qianting He, Shuai Li, Caihua Zhang, Yizhou Jiang, Qianming Chen, Anxun Wang, Demeng Chen
Format: Article
Language:English
Published: Wiley 2022-03-01
Series:Cancer Communications
Subjects:
head and neck squamous cell carcinoma
m7G modification
metastasis
METTL1
microenvironment
PI3K/AKT/mTOR signaling
Online Access:https://doi.org/10.1002/cac2.12273

Internet

https://doi.org/10.1002/cac2.12273

Similar Items