Identification and Functional Analysis of a Novel <i>CTNNB1</i> Mutation in Pediatric Medulloblastoma

Identification and Functional Analysis of a Novel <i>CTNNB1</i> Mutation in Pediatric Medulloblastoma

Medulloblastoma is the primary malignant tumor of the Central Nervous System (CNS) most common in pediatrics. We present here, the histological, molecular, and functional analysis of a cohort of 88 pediatric medulloblastoma tumor samples. The WNT-activated subgroup comprised 10% of our cohort, and a...

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Bibliographic Details
Main Authors: Lide Alaña, Caroline E. Nunes-Xavier, Laura Zaldumbide, Idoia Martin-Guerrero, Lorena Mosteiro, Piedad Alba-Pavón, Olatz Villate, Susana García-Obregón, Hermenegildo González-García, Raquel Herraiz, Itziar Astigarraga, Rafael Pulido, Miguel García-Ariza
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cancers
Subjects:
medulloblastoma
<i>CTNNB1</i>
β-catenin
mutation
Online Access:https://www.mdpi.com/2072-6694/14/2/421

Internet

https://www.mdpi.com/2072-6694/14/2/421

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