Aging bone marrow mesenchymal stromal cells have altered membrane glycerophospholipid composition and functionality[S]

Aging bone marrow mesenchymal stromal cells have altered membrane glycerophospholipid composition and functionality[S]

Human mesenchymal stem/stromal cells (hMSC) are increasingly used in advanced cellular therapies. The clinical use of hMSCs demands sequential cell expansions. As it is well established that membrane glycerophospholipids (GPL) provide precursors for signaling lipids that modulate cellular functions,...

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Bibliographic Details
Main Authors: Lotta Kilpinen, Feven Tigistu-Sahle, Sofia Oja, Dario Greco, Amarjit Parmar, Päivi Saavalainen, Janne Nikkilä, Matti Korhonen, Petri Lehenkari, Reijo Käkelä, Saara Laitinen
Format: Article
Language:English
Published: Elsevier 2013-03-01
Series:Journal of Lipid Research
Subjects:
glycerophospholipid profile
mesenchymal stem cell
arachidonic acid
docosahexaenoic acid
lipid signaling
mass spectrometry
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520419285

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http://www.sciencedirect.com/science/article/pii/S0022227520419285

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