The Role of cAMP in Beta Cell Stimulus–Secretion and Intercellular Coupling

The Role of cAMP in Beta Cell Stimulus–Secretion and Intercellular Coupling

Pancreatic beta cells secrete insulin in response to stimulation with glucose and other nutrients, and impaired insulin secretion plays a central role in development of diabetes mellitus. Pharmacological management of diabetes includes various antidiabetic drugs, including incretins. The incretin ho...

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Bibliographic Details
Main Authors: Andraž Stožer, Eva Paradiž Leitgeb, Viljem Pohorec, Jurij Dolenšek, Lidija Križančić Bombek, Marko Gosak, Maša Skelin Klemen
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cells
Subjects:
cAMP
beta cells
stimulus–secretion coupling
intercellular coupling
PKA
Epac2A
Online Access:https://www.mdpi.com/2073-4409/10/7/1658

Internet

https://www.mdpi.com/2073-4409/10/7/1658

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