Demography and the age of rare variants.

Large whole-genome sequencing projects have provided access to much rare variation in human populations, which is highly informative about population structure and recent demography. Here, we show how the age of rare variants can be estimated from patterns of haplotype sharing and how these ages can...

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Bibliographic Details
Main Authors: Iain Mathieson, Gil McVean
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4125085?pdf=render