Biological Role and Aberrant Overexpression of Syntenin-1 in Cancer: Potential Role as a Biomarker and Therapeutic Target

Biological Role and Aberrant Overexpression of Syntenin-1 in Cancer: Potential Role as a Biomarker and Therapeutic Target

Syntenin-1 is a 298 amino acid protein codified by the melanoma differentiation-associated gene-9 (<i>MDA-9</i>). Structurally, it is composed of four domains: N-terminal, PDZ1, PDZ2, and C-terminal. The PDZ domains of syntenin-1 are involved in the stability and interaction with other m...

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Bibliographic Details
Main Authors: Valeria Guadalupe Pintor-Romero, Edgar Hurtado-Ortega, María Lilia Nicolás-Morales, Mayralina Gutiérrez-Torres, Amalia Vences-Velázquez, Carlos Ortuño-Pineda, Mónica Espinoza-Rojo, Napoleón Navarro-Tito, Karen Cortés-Sarabia
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Biomedicines
Subjects:
syntenin-1
cancer
therapeutic target
biomarker
Online Access:https://www.mdpi.com/2227-9059/11/4/1034

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https://www.mdpi.com/2227-9059/11/4/1034

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