Hepatic Snai1 and Snai2 promote liver regeneration and suppress liver fibrosis in mice

Summary: Liver injury stimulates hepatocyte replication and hepatic stellate cell (HSC) activation, thereby driving liver regeneration. Aberrant HSC activation induces liver fibrosis. However, mechanisms underlying liver regeneration and fibrosis remain poorly understood. Here, we identify hepatic S...

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Bibliographic Details
Main Authors: Pingping Wang, Qianqian Kang, Wen-Shu Wu, Liangyou Rui
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724002031