Relevance of <i>CYP2D6</i> Gene Variants in Population Genetic Differentiation

Relevance of <i>CYP2D6</i> Gene Variants in Population Genetic Differentiation

A significant portion of the variability in complex features, such as drug response, is likely caused by human genetic diversity. One of the highly polymorphic pharmacogenes is <i>CYP2D6</i>, encoding an enzyme involved in the metabolism of about 25% of commonly prescribed drugs. In a di...

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Bibliographic Details
Main Authors: Anita Stojanović Marković, Matea Zajc Petranović, Tatjana Škarić-Jurić, Željka Celinšćak, Maja Šetinc, Željka Tomas, Marijana Peričić Salihović
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Pharmaceutics
Subjects:
<i>CYP2D6</i> gene
polymorphism
haplotype
star allele
pharmacogenetics
1000 Genomes populations
Online Access:https://www.mdpi.com/1999-4923/14/11/2481

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https://www.mdpi.com/1999-4923/14/11/2481

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