The thrombin generation capability of the Chacma baboon (Papio ursinus): implications for haemostatic disease models

Abstract Baboon models are often used to investigate haemostatic diseases, such as acquired thrombotic thrombocytopenic purpura or bacterial sepsis-induced disseminated intravascular coagulation, and their potential treatment with novel drugs. Thrombin generation is vital for these models, and an im...

Full description

Bibliographic Details
Main Authors: J. Joubert, S. M. Meiring, W. J. Janse van Rensburg
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-50341-8