Unlocking the role of lactate: metabolic pathways, signaling, and gene regulation in postmitotic retinal cells

The Warburg effect, which was first described a century ago, asserts that mitotic tumor cells generate higher quantities of lactate. Intriguingly, even in typical physiological circumstances, postmitotic retinal photoreceptor cells also produce elevated levels of lactate. Initially classified as met...

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Bibliographic Details
Main Authors: Raju V. S. Rajala, Ammaji Rajala
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Ophthalmology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fopht.2023.1296624/full