Longitudinal DNA methylation analysis of adult-type IDH-mutant gliomas

Longitudinal DNA methylation analysis of adult-type IDH-mutant gliomas

Abstract Diffuse gliomas are the most prevalent malignant primary brain tumors in adults and remain incurable despite standard therapy. Tumor recurrence is currently inevitable, which contributes to a persistent high morbidity and mortality in these patients. In this study, we examined the genome-wi...

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Bibliographic Details
Main Authors: Sandra Ferreyra Vega, Thomas Olsson Bontell, Teresia Kling, Asgeir Store Jakola, Helena Carén
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Acta Neuropathologica Communications
Subjects:
IDH-mutant gliomas
DNA methylation profiling
Tumor recurrence
Longitudinal analysis
Online Access:https://doi.org/10.1186/s40478-023-01520-1

Internet

https://doi.org/10.1186/s40478-023-01520-1

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