Patient-derived organoid culture of gastric cancer for disease modeling and drug sensitivity testing

Background: Gastric cancer treatment is complicated by the molecular heterogeneity of human tumor cells, which limits the efficacy of standard therapy and necessitates the need for personalized treatment development. Patient-derived organoids (PDOs) are promising preclinical cancer models, exhibitin...

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Bibliographic Details
Main Authors: Ming Zu, Xinyu Hao, Jing Ning, Xin Zhou, Yueqing Gong, Yanfei Lang, Weichao Xu, Jing Zhang, Shigang Ding
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223005401