LILRA2 selectively modulates LPS-mediated cytokine production and inhibits phagocytosis by monocytes.

LILRA2 selectively modulates LPS-mediated cytokine production and inhibits phagocytosis by monocytes.

The activating immunoglobulin-like receptor, subfamily A, member 2 (LILRA2) is primarily expressed on the surface of cells of the innate immunity including monocytes, macrophages, neutrophils, basophils and eosinophils but not on lymphocytes and NK cells. LILRA2 cross-linking on monocytes induces pr...

Full description

Bibliographic Details
Main Authors: Hao K Lu, Ainslie Mitchell, Yasumi Endoh, Taline Hampartzoumian, Owen Huynh, Luis Borges, Carolyn Geczy, Katherine Bryant, Nicodemus Tedla
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3316576?pdf=render

Similar Items

Similar Items