The adaptive landscape of wildtype and glycosylation-deficient populations of the industrial yeast Pichia pastoris

Abstract Background The effects of long-term environmental adaptation and the implications of major cellular malfunctions are still poorly understood for non-model but biotechnologically relevant species. In this study we performed a large-scale laboratory evolution experiment with 48 populations of...

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Bibliographic Details
Main Authors: Josef W. Moser, Iain B. H. Wilson, Martin Dragosits
Format: Article
Language:English
Published: BMC 2017-08-01
Series:BMC Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12864-017-3952-7