1,3,4-Oxadiazole <i>N</i>-Mannich Bases: Synthesis, Antimicrobial, and Anti-Proliferative Activities

1,3,4-Oxadiazole <i>N</i>-Mannich Bases: Synthesis, Antimicrobial, and Anti-Proliferative Activities

The reaction of 5-(3,4-dimethoxyphenyl)-1,3,4-oxadiazole-2(3<i>H</i>)-thione <b>3</b> with formaldehyde solution and primary aromatic amines or 1-substituted piperazines, in ethanol at room temperature yielded the corresponding <i>N</i>-Mannich bases 3-arylaminome...

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Bibliographic Details
Main Authors: Lamya H. Al-Wahaibi, Ahmed A. B. Mohamed, Samar S. Tawfik, Hanan M. Hassan, Ali A. El-Emam
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Molecules
Subjects:
1,3,4-oxadiazoles
<i>N</i>-Mannich bases
antimicrobial activity
anti-proliferative activity
Online Access:https://www.mdpi.com/1420-3049/26/8/2110

Internet

https://www.mdpi.com/1420-3049/26/8/2110

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