Polymorph Impact on the Bioavailability and Stability of Poorly Soluble Drugs

Drugs with low water solubility are predisposed to poor and variable oral bioavailability and, therefore, to variability in clinical response, that might be overcome through an appropriate formulation of the drug. Polymorphs (anhydrous and solvate/hydrate forms) may resolve these bioavailability pro...

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Bibliographic Details
Main Authors: Roberta Censi, Piera Di Martino
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/20/10/18759