Para-Substituted <i>O</i>-Benzyl Sulfohydroxamic Acid Derivatives as Redox-Triggered Nitroxyl (HNO) Sources

Nitroxyl shows a unique biological profile compared to the gasotransmitters nitric oxide and hydrogen sulfide. Nitroxyl reacts with thiols as an electrophile, and this redox chemistry mediates much of its biological chemistry. This reactivity necessitates the use of donors to study nitroxyl’s chemis...

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Bibliographic Details
Main Authors: Yueming Long, Zijun Xia, Allison M. Rice, S. Bruce King
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/27/16/5305