Retinoic Acid-Differentiated Neuroblastoma SH-SY5Y Is an Accessible In Vitro Model to Study Native Human Acid-Sensing Ion Channels 1a (ASIC1a)

Retinoic Acid-Differentiated Neuroblastoma SH-SY5Y Is an Accessible In Vitro Model to Study Native Human Acid-Sensing Ion Channels 1a (ASIC1a)

Human neuroblastoma SH-SY5Y is a prominent neurobiological tool used for studying neuropathophysiological processes. We investigated acid-sensing (ASIC) and transient receptor potential vanilloid-1 (TRPV1) and ankyrin-1 (TRPA1) ion channels present in untreated and differentiated neuroblastoma SH-SY...

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Bibliographic Details
Main Authors: Aleksandr P. Kalinovskii, Dmitry I. Osmakov, Sergey G. Koshelev, Kseniya I. Lubova, Yuliya V. Korolkova, Sergey A. Kozlov, Yaroslav A. Andreev
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Biology
Subjects:
acid-sensing ion channel (ASIC)
neuroblastoma SH-SY5Y
neuronal differentiation
dopaminergic neurons
retinoic acid
drug development
Online Access:https://www.mdpi.com/2079-7737/11/2/167

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https://www.mdpi.com/2079-7737/11/2/167

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