Experimental and theoretical studies on the synthesis of 1,4,5-trisubstituted pyrrolidine-2,3-diones

Substituted 4-acetyl-3-hydroxy-3-pyrroline-2-ones have been prepared via three-component reactions and the tautomerism of these 3-pyrroline-2-ones is due to the slight difference of energy, and the significantly large rate constant of transformation between two tautomers. 1,4,5-Trisubstituted pyrrol...

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Bibliographic Details
Main Authors: Nguyen Tran Nguyen, Vo Viet Dai, Nguyen Ngoc Tri, Luc Van Meervelt, Nguyen Tien Trung, Wim Dehaen
Format: Article
Language:English
Published: Beilstein-Institut 2022-08-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.18.118