Genetic Ancestry Estimates within Dutch Family Units and Across Genotyping Arrays: Insights from Empirical Analysis Using Two Estimation Methods

Genetic Ancestry Estimates within Dutch Family Units and Across Genotyping Arrays: Insights from Empirical Analysis Using Two Estimation Methods

Accurate inference of genetic ancestry is crucial for population-based association studies, accounting for population heterogeneity and structure. This study analyzes genome-wide SNP data from the Netherlands Twin Register to compare genetic ancestry estimates. The focus is on the comparison of ance...

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Bibliographic Details
Main Authors: Jeffrey J. Beck, Talitha Ahmed, Casey T. Finnicum, Koos Zwinderman, Erik A. Ehli, Dorret I. Boomsma, Jouke Jan Hottenga
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Genes
Subjects:
within-family analysis
genetic ancestry estimation
population structure
principal components analysis (PCA)
ADMIXTURE
Online Access:https://www.mdpi.com/2073-4425/14/7/1497

Internet

https://www.mdpi.com/2073-4425/14/7/1497

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