Skeletal muscle gene expression dysregulation in long-term spaceflights and aging is clock-dependent
Abstract The circadian clock regulates cellular and molecular processes in mammals across all tissues including skeletal muscle, one of the largest organs in the human body. Dysregulated circadian rhythms are characteristic of aging and crewed spaceflight, associated with, for example, musculoskelet...
Auteurs principaux: | , , , , |
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Format: | Article |
Langue: | English |
Publié: |
Nature Portfolio
2023-04-01
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Collection: | npj Microgravity |
Accès en ligne: | https://doi.org/10.1038/s41526-023-00273-4 |