Role of phase partitioning in coordinating DNA damage response: focus on the Apurinic Apyrimidinic Endonuclease 1 interactome

Role of phase partitioning in coordinating DNA damage response: focus on the Apurinic Apyrimidinic Endonuclease 1 interactome

Liquid-liquid phase separation (LLPS) is a way to concentrate biochemical reactions while excluding noninteracting components. Disordered domains of proteins, as well as interaction with RNA, favor condensation but are not mandatory for modulating this process. Recent insights about phase-separation...

Full description

Bibliographic Details
Main Authors: Tosolini Damiano, Antoniali Giulia, Dalla Emiliano, Tell Gianluca
Format: Article
Language:English
Published: De Gruyter 2020-12-01
Series:Biomolecular Concepts
Subjects:
base excision repair
bioinformatics
interactome
phase-separation
rna
Online Access:https://doi.org/10.1515/bmc-2020-0019

Internet

https://doi.org/10.1515/bmc-2020-0019

Similar Items