Microbiota profiling reveals alteration of gut microbial neurotransmitters in a mouse model of autism-associated 16p11.2 microduplication

Microbiota profiling reveals alteration of gut microbial neurotransmitters in a mouse model of autism-associated 16p11.2 microduplication

The gut-brain axis is evident in modulating neuropsychiatric diseases including autism spectrum disorder (ASD). Chromosomal 16p11.2 microduplication 16p11.2dp/+ is among the most prevalent genetic copy number variations (CNV) linked with ASD. However, the implications of gut microbiota status underl...

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Bibliographic Details
Main Authors: Zhang Fu, Xiuyan Yang, Youheng Jiang, Xinliang Mao, Hualin Liu, Yanming Yang, Jia Chen, Zhumei Chen, Huiliang Li, Xue-Song Zhang, Xinjun Mao, Ningning Li, Dilong Wang, Jian Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Microbiology
Subjects:
ASD
16p11.2
gut microbiota
16S rRNA
metabolomic
histamine
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1331130/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2024.1331130/full

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