Genetic Polymorphisms of <i>ENPP2</i> Are Possibly Associated with Pain Severity and Opioid Dose Requirements in Patients with Inflammatory Pain Conditions: Clinical Observation Study

Genetic Polymorphisms of <i>ENPP2</i> Are Possibly Associated with Pain Severity and Opioid Dose Requirements in Patients with Inflammatory Pain Conditions: Clinical Observation Study

Autotaxin, encoded by the <i>ENPP2</i> gene, is a known key element of neuropathic pain; however, its involvement in nociceptive pain processing remains unclear. We explored the associations between postoperative pain intensity, 24-h postoperative opioid dose requirements, and 93 <i&g...

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Bibliographic Details
Main Authors: Rikuhei Tsuchida, Daisuke Nishizawa, Ken-ichi Fukuda, Tatsuya Ichinohe, Kuniyuki Kano, Makoto Kurano, Kazutaka Ikeda, Masahiko Sumitani
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
autotaxin
genetic polymorphisms
nociceptive pain
opioid requirement
Online Access:https://www.mdpi.com/1422-0067/24/8/6986

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https://www.mdpi.com/1422-0067/24/8/6986

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