miR-27b-mediated suppression of aquaporin-11 expression in hepatocytes reduces HCV genomic RNA levels but not viral titers

miR-27b-mediated suppression of aquaporin-11 expression in hepatocytes reduces HCV genomic RNA levels but not viral titers

Abstract Background MicroRNAs (miRNAs) have gained much attention as cellular factors regulating hepatitis C virus (HCV) infection. miR-27b has been shown to regulate HCV infection in the hepatocytes via various mechanisms that have not been fully elucidated. In this study, therefore, we examined th...

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Bibliographic Details
Main Authors: Fuminori Sakurai, Rina Hashimoto, Chieko Inoue, Keisaku Wakabayashi, Tomohito Tsukamoto, Tsutomu Imaizumi, Taracena Gandara Marcos Andres, Eiko Sakai, Kanae Itsuki, Naoya Sakamoto, Takaji Wakita, Hiroyuki Mizuguchi
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Virology Journal
Subjects:
microRNA
HCV
miR-27b
Aquaporin-11
Online Access:http://link.springer.com/article/10.1186/s12985-019-1160-6

Internet

http://link.springer.com/article/10.1186/s12985-019-1160-6

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