Anillin regulates epithelial cell mechanics by structuring the medial-apical actomyosin network

Anillin regulates epithelial cell mechanics by structuring the medial-apical actomyosin network

Cellular forces sculpt organisms during development, while misregulation of cellular mechanics can promote disease. Here, we investigate how the actomyosin scaffold protein anillin contributes to epithelial mechanics in Xenopus laevis embryos. Increased mechanosensitive recruitment of vinculin to ce...

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Bibliographic Details
Main Authors: Torey R Arnold, Joseph H Shawky, Rachel E Stephenson, Kayla M Dinshaw, Tomohito Higashi, Farah Huq, Lance A Davidson, Ann L Miller
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-01-01
Series:eLife
Subjects:
anillin
epithelium
laser ablation
actin
tissue mechanics
contractility
Online Access:https://elifesciences.org/articles/39065

Internet

https://elifesciences.org/articles/39065

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