NHE7 upregulation potentiates the uptake of small extracellular vesicles by enhancing maturation of macropinosomes in hepatocellular carcinoma

NHE7 upregulation potentiates the uptake of small extracellular vesicles by enhancing maturation of macropinosomes in hepatocellular carcinoma

Abstract Background Small extracellular vesicles (sEVs) mediate intercellular communication that contributes to hepatocellular carcinoma (HCC) progression via multifaceted pathways. The success of cell entry determines the effect of sEV on recipient cells. Here, we aimed to delineate the mechanisms...

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Bibliographic Details
Main Authors: Yue Yao, Yi Xu, Liang Yu, Ting‐Mao Xue, Zhi‐Jie Xiao, Pui‐Chi Tin, Hiu‐Ling Fung, Hoi‐Tang Ma, Jing‐Ping Yun, Judy Wai Ping Yam
Format: Article
Language:English
Published: Wiley 2024-02-01
Series:Cancer Communications
Subjects:
hepatocellular carcinoma
small extracellular vesicles
macropinocytosis
pH regulation
sodium‐hydrogen exchanger
Online Access:https://doi.org/10.1002/cac2.12515

Internet

https://doi.org/10.1002/cac2.12515

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