Substance P is a mechanoresponsive, autocrine regulator of human tenocyte proliferation.

It has been hypothesised that substance P (SP) may be produced by primary fibroblastic tendon cells (tenocytes), and that this production, together with the widespread distribution of the neurokinin-1 receptor (NK-1 R) in tendon tissue, could play an important role in the development of tendinopathy...

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Bibliographic Details
Main Authors: Ludvig J Backman, Gloria Fong, Gustav Andersson, Alexander Scott, Patrik Danielson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3206074?pdf=render