Substance P is a mechanoresponsive, autocrine regulator of human tenocyte proliferation.
It has been hypothesised that substance P (SP) may be produced by primary fibroblastic tendon cells (tenocytes), and that this production, together with the widespread distribution of the neurokinin-1 receptor (NK-1 R) in tendon tissue, could play an important role in the development of tendinopathy...
Main Authors: | Ludvig J Backman, Gloria Fong, Gustav Andersson, Alexander Scott, Patrik Danielson |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3206074?pdf=render |
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