MOR promotes epithelial-mesenchymal transition and proliferation via PI3K/AKT signaling pathway in human colorectal cancer

MOR promotes epithelial-mesenchymal transition and proliferation via PI3K/AKT signaling pathway in human colorectal cancer

The mu-opioid receptor (MOR), a membrane-bound G protein-coupled receptor, is implicated in progression and long-term outcome of several types of tumors. However, the expression and clinical significance of MOR in colorectal cancer (CRC) remain unclear. In this study, a total of 180 paraffin-embedde...

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Bibliographic Details
Main Authors: Gao Lingling, Yang Li, He Yiping, Liu Yi, Xu Pinbo, Zhang Jun, Dai Sailin, Luo Xing, Sun Zhirong
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2022-08-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
colorectal cancer
mu-opioid receptor
epithelial-mesenchymal transition
PI3K/AKT signaling pathway
prognosis
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2022114

Internet

https://www.sciengine.com/doi/10.3724/abbs.2022114

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