Yttrium chloride induces ferroptosis in cardiomyocytes via iron accumulation and triggers cardiac lipid peroxidation and inflammation that cause heart adverse events in mice

Yttrium chloride induces ferroptosis in cardiomyocytes via iron accumulation and triggers cardiac lipid peroxidation and inflammation that cause heart adverse events in mice

The growing presence of yttrium (Y) in the environment raises concern regarding its safety and toxicity. However, limited toxicological data are available to determine cardiotoxicity of Y and its underlying mechanisms. In the present study, yttrium chloride (YCl3) intervention with different doses w...

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Bibliographic Details
Main Authors: Liang Xiong, Jinyu Huang, Chunmei Wu, Qiong Yuan, Sihui Wang, Liye Zhu, Zilu Li, Ziyue Sun, Yi Fang, Weisong Li, Gonghua Hu
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Yttrium
Lipid peroxide
Inflammation
Ferroptosis
Cardiac dysfunction
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323007832

Internet

http://www.sciencedirect.com/science/article/pii/S0147651323007832

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