A Comprehensive 2D-LC/MS Online Platform for Screening of Acetylcholinesterase Inhibitors

The continuous interest in discovering new bioactive molecules derived from natural products (NP) has stimulated the development of improved screening assays to help overcome challenges in NP-based drug discovery. Here, we describe a unique platform for the online screening of acetylcholinesterase i...

Full description

Bibliographic Details
Main Authors: Claudia Seidl, Juliana Maria de Lima, Gabriel Mazzi Leme, Ananda Ferreira Pires, Dwight R. Stoll, Carmen Lúcia Cardoso
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.868597/full