Cholesterol Corrects Altered Conformation of MHC-II Protein in Leishmania donovani Infected Macrophages: Implication in Therapy.

<h4>Background</h4>Previously we reported that Kala-azar patients show progressive decrease in serum cholesterol as a function of splenic parasite burden. Splenic macrophages (MΦ) of Leishmania donovani (LD) infected mice show decrease in membrane cholesterol, while LD infected macrophag...

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Detalles Bibliográficos
Main Authors: Koushik Roy, Sapan Mandloi, Saikat Chakrabarti, Syamal Roy
Formato: Artigo
Idioma:English
Publicado: Public Library of Science (PLoS) 2016-05-01
Series:PLoS Neglected Tropical Diseases
Acceso en liña:https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0004710&type=printable