Menin Maintains Cholesterol Content in Colorectal Cancer via Repression of LXR-Mediated Transcription

Menin Maintains Cholesterol Content in Colorectal Cancer via Repression of LXR-Mediated Transcription

Background and Aims: Menin is a nuclear scaffold protein that regulates gene transcription in an oftentimes tissue-specific manner. Our previous work showed that menin is over-expressed in colorectal cancer (CRC); however, the full spectrum of menin function in colonic neoplasia remains unclear. Her...

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Bibliographic Details
Main Authors: Thomas E. Nyul, Keely Beyries, Taylor Hojnacki, Rebecca Glynn, Kayla E. Paulosky, Anitej Gedela, Ariana Majer, Lily Altman, Kole H. Buckley, Zijie Feng, Kunfeng Sun, Zhicheng Peng, John W. Tobias, Xianxin Hua, Bryson W. Katona
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Cancers
Subjects:
menin
LXR
colorectal cancer
cholesterol
ABCA1
ABCG1
Online Access:https://www.mdpi.com/2072-6694/15/16/4126

Internet

https://www.mdpi.com/2072-6694/15/16/4126

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