Integrated single-cell and bulk RNA sequencing analyses reveal a prognostic signature of cancer-associated fibroblasts in head and neck squamous cell carcinoma

Integrated single-cell and bulk RNA sequencing analyses reveal a prognostic signature of cancer-associated fibroblasts in head and neck squamous cell carcinoma

Objectives: To identify a prognosis-related subtype of cancer-associated fibroblasts (CAFs) in head and neck squamous cell carcinoma (HNSCC) and comprehend its contributions to molecular characteristics, immune characteristics, and their potential benefits in immunotherapy and chemotherapy for HNSCC...

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Bibliographic Details
Main Authors: Yichen Yang, Ben Ma, Litao Han, Weibo Xu, Xiaoxue Du, Wenjun Wei, Tian Liao, Qinghai Ji, Ning Qu, Yu Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Genetics
Subjects:
head and neck carcinoma
cancer-associated fibroblast
single-cell sequencing
prognostic signature
bulk RNA sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.1028469/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.1028469/full

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