Analysis of cellular behavior and cytoskeletal dynamics reveal a constriction mechanism driving optic cup morphogenesis

Contractile actomyosin networks have been shown to power tissue morphogenesis. Although the basic cellular machinery generating mechanical tension appears largely conserved, tensions propagate in unique ways within each tissue. Here we use the vertebrate eye as a paradigm to investigate how tensions...

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Bibliographic Details
Main Authors: María Nicolás-Pérez, Franz Kuchling, Joaquín Letelier, Rocío Polvillo, Jochen Wittbrodt, Juan R Martínez-Morales
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-10-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/15797